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• Department
  • Geroscience Research Center
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About the department

Department of Chemical Biology

1. Identification of longevity regulated protein
2. Identification of longevity regulated protein degrader
3. Development of anti-aging chemical(s) which degrade specific protein regulating longevity

Research Focus

A. Bioactive small molecule signaling

• A1) Arginine target protein → UGGT1, glucokinase, cereblon
• A2) UDP glucose target protein → glucokinase, hexokinase

B. Glycolysis regulating chemical with new mechanism

• Glucose metabolism deficiency for elderly people and diabetes patients
• Cancer

C. Liver regeneration accelerator

• C1) Estrogen-ESR1
• C2) Chorionic gonadotropin
• C3) Third unknown protein

Members

Professor	Takeshi Imai
Research Fellow	Yuki Oiwa

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