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Shunki Itadera, Tadayoshi Aoyama, Yasuhisa Hasegawa, Keita Aimoto, Kenji Kato, Izumi Kondo : A clinical pilot study on posture stabilization via light contact with cane‑type companion. Robomech J 6, 17 https://doi.org/10.1186/s40648-019-0145-y , Nov 27 2019.
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KeikoYamada, Yoichi Ito, Masao Akagi, Etsuo Chosa, Takeshi Fuji, Kenichi Hirano, Shinichi Ikeda, Hideaki Ishibashi, Yasuyuki Ishibashi, Muneaki Ishijima, Eiji Ito, Norimasa Iwasaki, Ryoichi Izumida, Ken Kadoya, Masayuki Kamimura, Arihiko Kanaji, Hiroyuki Kato, Shunji Kishida, Takashi Ohe. Reference values for the locomotive syndrome risk test quantifying mobility of 8681 adults aged 20–89 years: A cross-sectional nationwide study in Japan. Journal of Orthopaedic Science. 2020 Nov;25(6):1084-1092. doi: 10.1016/j.jos.2020.01.011. Epub 2020 Mar 12.
Morita Y, Ito H, Torii M, Hanai A, Furu M, Hashimoto M, Tanaka M, Azukizawa M, Arai H, Mimori T, Matsuda S. Factors Affecting Walking Ability in Female Patients with Rheumatoid Arthritis. PLOS one 13(3):e0195059 2018.
Hanai A, Ishiguro H, Sozu T, Tsuda M, Yano I, Nakagawa T, Imai S, Hamabe Y, Toi M, Arai H, Tsuboyama T. Effects of Cryotherapy on Objective and Subjective Symptoms of Paclitaxel-Induced Neuropathy: Prospective Self-Controlled Trial. JNCI Volume 110, Issue 2 2018.
Fujita K, Otsuka T, Kawabata T, Sakai G, Matsushima-Nishiwaki R, Kozawa O, Tokuda H. Inhibitors of heat shock protein 90 (HSP90; HSPC) augment endothelin-1-induced heat shock protein27 (HSP27; HSPB1) through SAPK/JNK in osteoblasts. Mol. Med. Rep. 2018;17:8542-8547.
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Kinoshita K, Satake S, Matsui Y, Kawashima S, Arai H. Effect of β-hydroxy-β-methylbutyrate (hmb) on muscle strength in older adults with low physical function. JARCP 2019;8:1-6.
Harada-Shiba M, Arai H, Ishigaki Y, Ishibashi S, Okamura T, Ogura M, Dobashi K, Nohara A, Bujo H, Miyauchi K, Yamashita S, Yokote K; Working Group by Japan Atherosclerosis Society for Making Guidance of Familial Hypercholesterolemia Guidelines for Diagnosis and Treatment of Familial Hypercholesterolemia 2017. J Atheoscler Thromb 2018 Aug 1;25(8):751-770. doi:10.5551/jat.CR003. Epub 2018 Jun 7.
Arai H, Wakabayashi H, Yoshimura Y, Yamada M, Kim H, Harada A. Chapter 4 Treatment of sarcopenia. Geriatr Gerontol Int 18 Suppl 1:28-44 2018.
Kuzuya M, Sugimoto K, Suzuki T, Watanabe Y, Kamibayashi K, Kurihara T, Fujimoto M, Arai H. Chapter 3 Prevention of sarcopenia. Geriatr Gerontol Int 18 Suppl 1:23-27 2018.
Shimokata H, Shimada H, Satake S, Endo N, Shibasaki K, Ogawa S, Arai H. Chapter 2 Epidemiology of sarcopenia. Geriatr Gerontol Int 18 Suppl 1:13-22 2018.
Akishita M, Kozaki K, Iijima K, Tanaka T, Shibasaki K, Ogawa S, Arai H. Chapter 1 Definitions and diagnosis of sarcopenia. Geriatr Gerontol Int 18 Suppl 1:7-12 2018.
Yamashita S, Masuda D, Arai H, Matsuzawa Y. Cultural Barriers in the Treatment of Dyslipidemia: A Survey of Japanese Physician Attitudes. J Atheoscler Thromb 2019 Feb 1;26(2):154-169. doi:10.5551/jat.44677. Epub 2018 May 18.
Suma S, Watanabe Y, Hirano H, Kimura A, Edahiro A, Awata S, Yamashita Y, Matsushita K, Arai H, Sakurai T. Factors Affecting the Appetites of Persons with Alzheimer's Disease and Mild Cognitive Impairment. Geriatr Gerontol Int 2018 Aug;18(8):1236-1243. doi: 10.1111/ggi.13455. Epub 2018 May 29.
Arai H, Yamashita S, Yokote K, Araki E, Suganami H, Ishibashi S. Efficacy and safety of pemafibrate versus fenofibrate in patients with high triglycerides and low HDL cholesterol Levels: A multicenter, placebo-controlled, double-blind, randomized trial. J Atheoscler Thromb. 2018 Jun 1;25(6):521-538. doi: 10.5551/jat.44412. Epub 2018 Apr 7.
Fougere B, Cesari M, Arai H, Woo J, Merchant RA, Flicker L, Cherubini A, Bauer JM, Vellas B, Morley JE. Involving Primary Care Health Professionals in Geriatric Assessment. J Nutr Health Aging. 22(5):566-568 2018.
Okura M, Ogita M, Yamamoto M, Nakai T, Numata T, Arai H. Community Activities Predict Disability and Mortality in Community-Dwelling Older Adults. Geriatr Gerontol Int. 2018 Jul;18(7):1114-1124.
Sugimoto T, Sakurai T, Ono R, Kimura A, Saji N, Niida S, Toba K, Chen LK, Arai. Epidemiological and Clinical Significance of Cognitive Frailty: a Mini Review. Ageing Research Reviews 44:1-7 2018.
Fujita K, Otsuka T, Kawabata T, Kainuma S, Sakai G, Matsushima-Nishiwaki R, Kozawa O, Tokuda H. HSP90 limits thrombin-stimulated IL-6 synthesis in osteoblast-like MC3T3-E1 cells: regulation of p38 MAPK. Int. J. Mol. Med. 2018;42:2185-2192.
Uematsu K, Enomoto Y, Onum T, Tsujimoto M, Doi T, Matsushima-Nishiwaki R, Tokuda H, Ogura S, Iida H, Kozawa O, Iwama T. Rac regulates the TRAP-induced phosphorylated-HSP27 release via p38 MAP kinase but not JNK from human platelets. Cell. Physiol. Biochem. 2018 Sep 13;49(4):1523-1538.
Kawabata T, Tokuda H, Sakai G, Fujita K, Matsushima-Nishiwaki R, Otsuka T, Kozawa O. Repression of IGF-I-induced osteoblast migration by (-)-epigallocatechin gallate through p44/p42 MAP kinase signaling. Biomed. Rep. 2018;9:318-326.
Arai H, Satake S, Kozaki K. Cognitive Frailty in Geriatrics. Clin Geriatr Med. 34(4):667-675 2018.
Yamada M, Kimura Y, Ishiyama D, Nishio N, Otobe Y, Tanaka T, Ohji S, Koyama S, Sato A, Suzuki M, Ogawa H, Ichikawa T, Ito D, Arai H. Phase angle is a useful indicator for muscle function in older adults. J Nutr Health Aging, 2019;23(3):251-255. doi: 10.1007/s12603-018-1151-0.
Yamada M, Arai H. Social frailty predicts incident disability and mortality among community-dwelling Japanese older adults. J Am Med Dir Assoc, 2018 Dec;19(12):1099-1103. doi: 10.1016/j.jamda.2018.09.013.
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Shimada H, Doi T, Lee S, Makizako H, Chen LK, Arai H. Cognitive frailty predicts incident dementia among community-dwelling older people J. Clin. Med 7(9):250 2018.
Toyoshima, Araki A, Tamura Y, Iritani O, Ogawa S, Kozaki K, Ebihara S, Hanyu H, Arai H, Kuzuya M, Iijima K, Sakurai T, Suzuki T, Toba K, Arai H, Akishita M, Rakugi H, Yokote K, Ito H, Awata S. Development of the Dementia Assessment Sheet for Community-based Integrated Care System 8-items, a short version of the Dementia Assessment Sheet for Community-based Integrated Care System 21-items, for the assessment of cognitive and daily functions Geriatr Gerontol Int 18(10):1458-1462, 2018.
Kitajima M, Miyata C, Tamura K, Kinoshita A, Arai H. Job satisfaction in certified nurse specialists and certified nurses in cancer care in Japan Clin. Pract. 15(SII):977-990 2018.
Torii M, Hashimoto M, Hanai A, Fujii T, Furu M, Ito H, Uozumi R, Hamaguchi M, Terao C, Yamamoto W, Uda M, Nin K, Morita S, Arai H, Mimori T. Prevalence of and factors associated with sarcopenia in patients with rheumatoid arthritis. Mod Rheumatol 11:1-7, 2018.
Kawabata T, Otsuka T, Fujita K, Sakai G, Kim W, Matsushima-Nishiwaki R, Kuroyanagi G, Kozawa O, Tokuda H. HSP70 inhibitors reduce the osteoblast migration by epidermal growth factor. Curr. Mol. Med. 2018 Dec 12. doi: 10.2174/1566524019666181213112847.
Matsuba I, Matsuba R, Ishibashi S, Yamashita S, Arai H, Yokote K, Suganami H, Araki E. Effects of a novel selective peroxisome proliferator-activated receptor-α modulator, pemafibrate, on hepatic and peripheral glucose uptake in patients with hypertriglyceridemia and insulin resistance. J Diabetes Investig 2018 Nov;9(6):1323-1332.
Harada-Shiba M, Ako J, Arai H, Hirayama A, Nohara A, Ozaki A, Uno K, Nakamura M. Prevalence of familial hypercholesterolemia in patients with acute coronary syndrome in Japan: results of the EXPLORE-J study. Atherosclerosis 2018 Oct;277:362-368.
Uematsu K, Enomoto Y, Onuma T, Tsujimoto M, Doi T, Matsushima-Nishiwaki R, Tokuda H, Ogura S, Iida H, Kozawa O, Iwama T. Rac regulates the TRAP-induced release of phosphorylated-HSP27 from human platelets via p38 MAP kinase but not JNK. Cell. Physiol. Biochem. 2018;49:1523-1538.
Okura M, Ogita M, Yamamoto M, Nakai T, Numata T, Arai H. Health checkup behavior and individual health beliefs in older adults. Geriatr Gerontol Int. 2018 Feb;18(2):338-351. doi: 10.1111/ggi.13169. Epub 2017 Sep 7.
Dent E, Lien C, Lim WS, Wong WC, Wong CH, Ng TP, Woo J, Dong B, de la Vega S, Hua Poi PJ, Kamaruzzaman SBB, Won C, Chen LK, Rockwood K, Arai H, Rodriguez-Mañas L, Cao L, Cesari M, Chan P, Leung E, Landi F, Fried LP, Morley JE, Vellas B, Flicker L. The Asia-Pacific Clinical Practice Guidelines for the Management of Frailty. J Am Med Dir Assoc. 2017;18(7):564-575.
Morley JE, Arai H, Cao L, Dong B, Merchant RA, Vellas B, Visvanathan R, Woo J. Integrated Care: Enhancing the Role of the Primary Health Care Professional in Preventing Functional Decline: A Systematic Review. J Am Med Dir Assoc. 2017;18(6):489-494.
Yamada M, Arai H. Self-Management Group Exercise Extends Healthy Life Expectancy in Frail Community-Dwelling Older Adults. Int J Environ Res Public Health 2017, 14(5):531.
Yamada M, Kimura Y, Ishiyama D, Nishio N, Abe Y, Kakehi T, Fujimoto J, Tanaka T, Ohji S, Otobe Y, Koyama S, Okajima Y, Arai H. Differential characteristics of skeletal muscle in community-dwelling older adults. J Am Med Dir Assoc. 2017 Sep 1;18(9):807.e9-807.e16. doi: 10.1016/j.jamda.2017.05.011. Epub 2017 Jul 1.
Madoka Ikemoto-Uezumi, Yasumoto Matsui, Masaki Hasegawa, Remi Fiujita,Yasuhide Kanayama, Akiyoshi Uezumi, Tsuyoshi Watanabe, Atsushi Harada, A.Robin Poole, Naohiro Hashimoto. Disuse Atrophy Accompanied by Intramuscular Ectopic Adipogenesis in Vastus Medialis Muscle of Advanced Osteoarthritis Patients. Am J Pathol. 2017 Dec;187(12):2674-2685. doi: 10.1016/j.ajpath.2017.08.009. Epub 2017 Sep 15.
Yoshihiro Yoshimura, Hidetaka Wakabayashi, Minoru Yamada, Hunkyung Kim, Atsushi Harada, Hidenori Arai. Interventions for treating sarcopenia: a systematic review and meta-analysis of randomized controlled studies. Journal of the American Medical Directors Association 18(6): 553.e1-553.e16, 2017.
Shigeo Kawada, Atsushi Harada, Naohiro Hashimoto. Impairment of cold injury-induced muscle regeneration in mice receiving a combination of bone fracture and alendronate treatment. PLOS ONE 12(7):e0181457, 2017.
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Satake S, Shimokata H, Senda K, Kodo I, Toba K. Validity of Total Kihon Checklist Score for Predicting the Incidence of 3-Year Dependency and Mortality in a Community-Dwelling Older Population. J Am Med Dir Assoc 18: 552.e1-552.e6.
Kuroyanagi G, Tokuda H, Yamamoto N, Kainuma S, Fujita K, Ohguchi R, Kawabata T, Sakai G, Matsushima-Nishiwaki R, Harada A, Kozawa O, Otsuka T. (-)-Epigallocatechin gallate synergistically potentiates prostaglandin E2-stimulated osteoprotegerin synthesis in osteoblasts. Prostaglandins Other Lipid Mediat. 2017;128-129:27-33.
Kuroyanagi G, Tokuda H, Yamamoto N, Kainuma S, Fujita K, Ohguchi R, Matsushima-Nishiwaki R, Kozawa O, Otsuka T. Attenuation of prostaglandin E1‑induced osteoprotegerin synthesis in osteoblasts by normoxic HIF inducers. Mol. Med. Rep. 2017;15:1847-1852.
Fujita K, Tokuda H, Yamamoto N, Kainuma S, Kawabata T, Sakai G, Kuroyanagi G, Matsushima-Nishiwaki R, Harada A, Kozawa O, Otsuka T. Incretins amplify TNF-a-stimulated IL-6 synthesis in osteoblasts: suppression of the IkB/NF-kB pathway. Int. J. Mol. Med. 2017;39:1053-1060.
Fujita K, Otsuka T, Yamamoto N, Kainuma S, Ohguchi R, Kawabata T, Sakai G, Kuroyanagi G, Matsushima-Nishiwaki R, Kozawa O, Tokuda H. (-)-Epigallocatechin gallate but not chlorogenic acid up-regulates osteoprotegerin synthesis by bone morphogenic protein-4 in osteoblasts. Exp. Ther. Med.2017;14:417-423.
Fujita K, Tokuda H, Kainuma S, Kuroyanagi G, Yamamoto N, Matsushima-Nishiwaki R, Harada A, Kozawa O, Otsuka T. Resveratrol suppresses thyroid hormone-induced osteocalcin synthesis in osteoblasts. Mol. Med. Rep. 2017;16:2881-2886.
Fujita K, Tokuda H, Kuroyanagi G, Yamamoto N, Kainuma S, Kawabata T, Sakai G, Matsushima-Nishiwaki R, Kozawa O, Otsuka T. HSP90 inhibitors potentiate PGF2a-induced IL-6 synthesis via p38 MAP kinase in osteoblasts. PLoS One. 2017;12(5):e0177878.
Onuma T, Tanabe K, Kito Y, Tsujimoto M, Uematsu K, Enomoto Y, Matsushima-Nishiwaki R, Doi T, Nagase K, Akamatsu S, Tokuda H, Ogura S, Iwama T, Kozawa O, Iida H. Sphingosine 1-phosphate (S1P) suppresses the collagen-induced activation of human platelets via S1P4 receptor. Thromb. Res. 2017;156:91-100.
Kainuma S, Tokuda H, Yamamoto N, Kuroyanagi G, Fujita K, Kawabata T, Sakai G, Matsushima-Nishiwaki R, Kozawa O, Otsuka T. Heat shock protein 27 (HSPB1) suppresses PDGF-BB-induced migration of osteoblasts. Int. J. Mol. Med. 2017 Oct;40(4):1057-1066. doi: 10.3892/ijmm.2017.3119. Epub 2017 Sep 1.
Ozaki K, Kondo I, Hirano S, Kagaya H, Saitoh E, Osawa A, Fujinori Y, Training with a balance exercise assist robot is more effective than conventional training for frail older adults. Geriatrics & Gerontology International. 2017 Nov;17(11):1982-1990. doi: 10.1111/ggi.13009. Epub 2017 Mar 10.
Hiroshi Hagino, Naoto Endo, Tetsuji Yamamoto, Atsushi Harada, Jun Iwamoto, Naoki Kondo, Tasuku Mashiba, Satoshi Mori, Junichi Nakamura, Seiji Ohtori, Akinori Sakai, Junichi Takada, Yoshiharu Kato. Treatment status and radiographic features of patients with atypical femoral fractures. Journal of Orthopaedic Science. 2018 Mar;23(2):316-320. doi: 10.1016/j.jos.2017.10.008.
Watanabe Y, Arai H, Hirano H, Morishita S, Ohara Y, Edahiro A, Murakami M, Shimada H, Kikutani T, Suzuki T. Oral function as an indexing parameter for mild cognitive impairment in older adults. Geriatr Gerontol Int. 2018 May;18(5):790-798. doi: 10.1111/ggi.13259. Epub 2018 Jan 30.
Teramoro T, Kai T, Ozaki A, Crawford B, Arai H, Yamashita S. Treatment Patterns and Lipid Profile in Patients with Familial Hypercholesterolemia in Japan. J Atheoscler Thromb. 2018 Jul 1;25(7):580-592. doi: 10.5551/jat.41483. Epub 2018 Jan 19.
Yamada M, Arai H. Is grip strength adjustment necessary for sarcopenia diagnosis? Geriatr Gerontol Int. 2018 Mar;18(3):511-512. doi: 10.1111/ggi.13232.
Eiko Takano, Keita Aimoto, Masanori Tanimoto, Toshio Teranishi, Naoki Itoh, Kenji Toba, Izumi Kondo. Comprehensive approach for community-based integrated care reduces risk of falls after fracture Journal of Frailty, Sarcopenia and Falls(2) 73-77; 2017/12
Sakai G, Otsuka T, Fujita K, Kainuma S, Kuroyanagi G, Kawabata T, Matsushima-Nishiwaki R, Kozawa O, Tokuda H. Amplification by (-) epigallocatechin gallate of prostaglandin F2-stimulated synthesis of osteoprotegerin in osteoblasts. Mol. Med. Rep. 2017;16:6376-6381.
Kawabata T, Tokuda H, Fujita K, Kainuma S, Sakai G, Matsushima-Nishiwaki R, Kozawa O, Otsuka T. Resveratorol inhibits the epidermal growth factor-induced migration of osteoblasts: The suppression of SAPK/JNK and Akt. Cell. Physiol. Biochem. 2017;43:1025-1036.
Kawabata T, Otsuka T, Fujita K, Kainuma S, Yamamoto N, Kuroyanagi G, Sakai G, Matsushima-Nishiwaki R, Kozawa O, Tokuda H. Suppression by HSP90 inhibitors of BMP-4-stimulated osteoprotegerin synthesis in osteoblasts: Attenuation of p70 S6 kinase. Mol. Med. Rep. 2017;16:8507-8512.
Sakai G, Tokuda H, Fujita K, Kainuma S, Kawabata T, Matsushima-Nishiwaki R, Kozawa O, Otsuka T. Heat shock protein 70 negatively regulates TGF--stimulated VEGF synthesis via p38 MAP kinase in osteoblasts. Cell. Physiol. Biochem. 2017;44:1133-1145.
Kawabata T, Otsuka T, Fujita K, Sakai G, Matsushima-Nishiwaki R, Kozawa O, Tokuda H.(-)-Epigallocatechin gallate but not chlorogenic acid suppresses EGF-stimulated migration of osteoblasts: attenuation of p38 MAPK activity. Inter. J. Mol. Med. 2018 Dec;42(6):3149-3156. doi: 10.3892/ijmm.2018.3884. Epub 2018 Sep 18.
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平野裕滋, 藤田 秀, 平野啓祐, 阿部 潤, 杉浦加奈子, 市原 薫, 松井康素. 日本転倒予防学会誌.4(1):43-51.四日市市における地域高齢者の転倒実態~2008年から2015年までの8年間の救急出動記録より~Rate of Falls by Community-Dwelling Older Adults in Yokkaichi City based on Emergency Dispatch Records for Eight Year from 2008 to 2015.