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研究関連

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研究関連

原著論文

  1. Fady S. Alnajjar, Juan C. Moreno, Ken-ichi Ozaki, Izumi Kondo, Shingo Shimoda : Motor Control System for Adaptation of Healthy Individuals and Recovery of Poststroke Patients: A Case Study on Muscle Synergies. Hindawi Neural Plasticity 2019, https://doi.org/10.1155/2019/8586416, 2019/3.
  2. Izumi Kondo : Frailty in an aging society and the applications of robots. Japanese Journal of Comprehensive Rahabilitation Science 10, 47-49, 31 May, 2019.
  3. Fujita K,Otsuka T, Kawabata T, Sakai G, Kim W, Matsushima-Nishiwaki R, Kozawa O, Tokuda H. Wnt3a downregulates thyroid hormone-induced osteocalcin expression in osteoblasts. Exp. Therapeut. Med. 2019 Sep;18(3):1921-1927. doi: 10.3892/etm.2019.7764. Epub 2019 Jul 10.
  4. Kawabata T, Tokuda H, Fujita K, Matsushima-Nishiwaki R, Sakai G, Tachi J, Kim W, Iida H, Otsuka T, Kozawa O. HSP90 inhibitors diminish PDGF-BB-induced migration of osteoblasts via suppression of p44/p42 MAP kinase.  Biomedical Res. 2019;40(4):169-178. doi: 10.2220/biomedres.40.169.
  5. Okura M, Ogita M, Kami town municipal office staff, Arai H. Self-reported cognitive frailty predicts adverse health outcomes for community-dwelling older adults based on an analysis of sex and age.  J Nutr Health Aging, 2019;23(7):654-664. doi: 10.1007/s12603-019-1217-7.
  6. Arai H, Mortaki K, Rane P, Quinn C, Zhao Z, Qian Y.  Estimating Years of Life Lost Due to Cardiovascular Disease in Japan.  Circ J 2019 Apr 25;83(5):1006-1010. doi: 10.1253/circj.CJ-18-1216. Epub 2019 Mar 26.
  7. Yamada M, Kimura Y, Ishiyama D, Nishio N, Otobe Y, Tanaka T, Ohji S, Koyama S, Sato A, Suzuki M, Ogawa H, Ichikawa T, Ito D, Arai H. Synergistic effect of body-weight resistance exercise and protein supplementation on skeletal muscle in sarcopenic or dynapenic older adults. Geriatr Gerontol Int. 2019 May;19(5):429-437. doi: 10.1111/ggi.13643. Epub 2019 Mar 13.
  8. Nishimura A, Harashima S, Hosoda K, Arai H and Inagaki N. Sex-related differences in frailty factors in order persons with type 2 diabetes: across-sectional study. Ther Adv Endocrinol Metab. 2019 Mar 5;10:2042018819833304. doi: 10.1177/2042018819833304. eCollection 2019.
  9. Yokote K, Yamashita S, Arai H, Araki E, Suganami H, Ishibashi S. Long-term efficacy and safety of pemafibrate, a novel selective peroxisome proliferator-activated receptor-α modulator (SPPARMα), in dyslipidemic patients with renal impairment. IJMS 2019 Feb 6;20(3):706. doi: 10.3390/ijms20030706.
  10. Yuki A, Otsuka R, Tange C, Nishita Y, Tomida M, Ando F, Shimokata H, Arai H. Daily physical activity predicts frailty development among community-dwelling older Japanese adults. J Am Med Dir Assoc. 2019 Aug;20(8):1032-1036. doi: 10.1016/j.jamda.2019.01.001. Epub 2019 Feb 18.
  11. Satake S, Shimokata H, Senda K, Kondo I, Arai H, Toba K. Predictive ability of seven domains of the Kihon Checklist for incident dependency and mortality. J Frailty Aging 2019;8(2):85-87. doi: 10.14283/jfa.2019.3.
  12. Koji Tsukasaki, Yasumoto Matsui, Hidenori Arai, Atsushi Harada, Makiko Tomida, Marie Takemura, Rei Otsuka, Fujiko Ando, Hiroshi Shimokata. Association of muscle strength and gait speed with cross-sectional muscle area determined by mid-thigh computed tomography - a comparison with skeletal muscle mass measured by dual-energy X-ray absorptiometry. The Journal of Frailty & Aging. 2020;9(2):82-89. doi: 10.14283/jfa.2020.16.
  13. Otsuka R, Kato Y, Tange C, Nishita Y, Tomida M, Imai T, Ando F, Shimokata H, Arai H. Protein intake per day and at each daily meal and skeletal muscle mass declines among older community dwellers in Japan. Public Health Nutr, 2020 Apr;23(6):1090-1097. doi: 10.1017/S1368980019002921. Epub 2019 Oct 14.
  14. Chou MY, Nishita Y, Nakagawa T, Tange C, Tomida M, Shimokata H, Otsuka R, Chen LK, Arai H. Role of Gait Speed and Grip Strength in Predicting 10-year Cognitive Decline among Community-dwelling Older People. BMC Geriatr, 5;19(1):186,2019.
  15. Ogama N, Sakurai T, Kawashima S, Tanikawa T, Tokuda H, Satake S,   Miura H, Shimizu A, Kokubo M, Niida S, Toba K, Umegaki H, Kuzuya M. Association of Glucose Fluctuations with Sarcopenia in Older Adults with Type 2 Diabetes Mellitus. J Clin Med. 2019;8(3). pii: E319. doi:10.3390/jcm8030319.
  16. Kim W, Tokuda H, Kawabata T, Fujita K, Sakai G, Nakashima D, Tachi J,   Kuroyanagi G, Matsushima-Nishiwaki R, Tanabe K, Otsuka T, Iida H,   Kozawa O. Enhancement by HSP90 inhibitor of PGD2-stimulated HSP27 induction in osteoblasts: suppression of SAPK/JNK and p38 MAP kinase. Prostaglandins Other Lipid Mediat. 2019:1;143:106327. doi: 10.1016/j.prostaglandins.
  17. Kito Y, Iida M, Tanabe K, Onuma T, Tsujimoto M, Nagase K, Tokuda H, Iwama T, Kozawa O, Iida H. Smoking cessation affects human platelet activation induced by collagen. Exp.Therapeut.Med. 2019 Nov;18(5):3809-3816. doi: 10.3892/etm.2019.8025. Epub 2019 Sep 18.
  18. Otsuka R, Tange C, Tomida M, Nishita Y, Kato Y, Yuki A, Ando F, Shimokata H, Arai H. Dietary factors associated with the development of physical frailty in community-dwelling older adults. J Nutr Health Aging. 2019;23(1):89-95, 2019.
  19. Nishida MM, Okura M, Ogita M, Aoyama T, Tsuboyama T, Arai H. Two-Year Weight Loss but Not Body Mass Index Predicts Mortality and Disability in an Older Japanese Community-Dwelling Population. J Am Med Dir Assoc. 20:1654.e11-1654.e18, 2019.
  20. Shunki Itadera, Tadayoshi Aoyama, Yasuhisa Hasegawa, Keita Aimoto, Kenji Kato, Izumi Kondo : A clinical pilot study on posture stabilization via light contact with cane‑type companion. Robomech J 6, 17 https://doi.org/10.1186/s40648-019-0145-y , Nov 27 2019.
  21. Tokuda H, Kusunose M, Senda K, Kojima K,Onuma T, Kojima A, Mizutani D, Enomoto Y, Iwama T, Iida H, Kozawa O. The release of phosphorylated-HSP27 from activated platelets of obstructive sleep apnea syndrome (OSAS) patients. Respir.Investig. 2020 Mar;58(2):117-127. doi: 10.1016/j.resinv.2019.10.006. Epub 2019 Dec 16.
  22. Auyeung TW, Arai H, Chen LK, Woo J. Normative date of handgrip strength in 26344 older adults - a pooled date set from eight cohorts in Asia. J Nutr Health Aging, 24, pages125–126 (2020).
  23. Kawabata T, Tokuda H, Kuroyanagi G, Fujita K, Sakai G, Kim W, Matsushima-Nishiwaki R, Iida H, Yata K, Wang S, Mizoguchi A, Otsuka T, Kozawa O. Incretin accelerates platelet-derived growth factor-BB-induced osteoblast migration via protein kinase A: The upregulation of p38 MAP kinase. Sci Rep. 2020 Feb 11;10(1):2341. 2020/02.
  24. Hidenori Arai, Koichi Kozaki, Masafumi Kuzuya, Yasumoto Matsui, Shosuke Satake. Clinical guide for frailty, Chapter2 Frailty concepts. GGI Vol.20(1). February 2020.
  25. Mizutani D, Onuma T, Tanabe K, Kojima A, Uematsu K, Nakashima D, Doi T, Enomoto Y, Matsushima-Nishiwaki R, Tokuda H, Ogura S, Iida H, Kozawa O, Iwama T. Olive polyphenol reduces the collagen-elicited release of phosphorylated HSP27 from human platelets. Biosci Biotechnol Biochem. 2020 Mar;84(3):536-543. doi: 10.1080/09168451.2019.1697196. Epub 2019 Nov 24.
  26. Onuma T, Iida M, Kito Y, Tanabe K, Kojima A, Nagase K, Uematsu K, Enomoto Y, Doi T, Tokuda H, Ogura S, Iwama T, Kozawa O, Iida H. Cigarette smoking cessation temporarily enhances the release of phosphorylated-HSP27 from human platelets. Intern. Med. 2020 Aug 1;59(15):1841-1847. doi: 10.2169/internalmedicine.4000-19. Epub 2020 Apr 30.
  27. Satake S, Kinoshita K, Matsui Y, Arai H. Physical Domain of the Kihon Checklist: A Possible Surrogate for Physical Function Tests. Geriatrics & Gerontology International. 2020 Jun;20(6):644-646. doi: 10.1111/ggi.13916.
  28. Sugimoto K, Rakugi H, Kojima T, Ishii S, Akishita M, Tamura Y, Araki A, Kozaki K, Senda K, Fukuoka H, Satake S, Arai H. Chapter 4 Frailty and specific diseases. Geriatr Gerontol Int 20 S1: 25-37, 2020.
  29. KeikoYamada, Yoichi Ito, Masao Akagi, Etsuo Chosa, Takeshi Fuji, Kenichi Hirano, Shinichi Ikeda, Hideaki Ishibashi, Yasuyuki Ishibashi, Muneaki Ishijima, Eiji Ito, Norimasa Iwasaki, Ryoichi Izumida, Ken Kadoya, Masayuki Kamimura, Arihiko Kanaji, Hiroyuki Kato, Shunji Kishida, Takashi Ohe. Reference values for the locomotive syndrome risk test quantifying mobility of 8681 adults aged 20–89 years: A cross-sectional nationwide study in Japan. Journal of Orthopaedic Science. 2020 Nov;25(6):1084-1092. doi: 10.1016/j.jos.2020.01.011. Epub 2020 Mar 12.

特許:出願ないし成立

  1. 松井康素、原田久光、特許第6578081号、起立着座移動支援装置、令和1年8月30日登録

メディア等紹介

  1. 近藤和泉、NHK 「きょうの健康」、平成31年4月30日(火)午後20時30~
  2. 近藤和泉、ロボットでリハビリ・介護・健康長寿、NHKテキスト、今日の健康 7, 92-93, 2019
  3. 松井康素、手足のしびれや排尿障害も 頸椎症性神経根症・脊髄症、新ロコモをとめよう(25)、『暮らすめいと』、2019年4月号、中日新聞東京本社発刊
  4. 松井康素、肩関節を大きく動かそう 五十肩(肩関節周囲炎)の治療、新ロコモをとめよう(26)、『暮らすめいと』、2019年5月号、中日新聞東京本社発刊
  5. 松井康素、腕を上げる途中の痛みは腱が悪い 肩関節を包む腱が切れる肩腱板損傷、新ロコモをとめよう(27)、『暮らすめいと』、2019年6月号、中日新聞東京本社発刊
  6. 松井康素、腕がほとんど動かせない 急で激烈な肩の痛み 石灰沈着性腱板炎、新ロコモをとめよう(28)、『暮らすめいと』、2019年7月号、中日新聞東京本社発刊
  7. 松井康素、肩甲骨を大きく動かそう 肩こりには僧帽筋の緊張をほぐす、新ロコモをとめよう(29)、『暮らすめいと』、2019年8月号、中日新聞東京本社発刊
  8. 松井康素、小指、薬指のしびれや変形 進行すると筋肉が痩せる 肘部管症候群、新ロコモをとめよう(30)、『暮らすめいと』、2019年9月号、中日新聞東京本社発刊
  9. 松井康素、「一生歩ける足」の作り方最新ガイド、女性自身、2019年9月3日号 p.71-77、光文社
  10. 松井康素、親指、人さし指がしびれる OKサインができない 手根管症候群、新ロコモをとめよう(31)、『暮らすめいと』、2019年10月号、中日新聞東京本社発刊
  11. 松井康素、曲げた指がバネのように戻る 指の使い過ぎに注意(ばね指=弾発指)、新ロコモをとめよう(32)、『暮らすめいと』、2019年11月号、中日新聞東京本社発刊
  12. 松井康素、親指の付け根の腫れと痛み 使い過ぎや老化が原因 母指CM関節症、新ロコモをとめよう(33)、『暮らすめいと』、2019年12月号、中日新聞東京本社発刊
  13. 松井康素、指の第一関節の腫れと痛み へバーデン結節 変形性関節症の一種、新ロコモをとめよう(34)、『暮らすめいと』、2020年1月号、中日新聞東京本社発刊
  14. 松井康素、「フレイル」を知っていますか 心身全体でみた要介護手前の状態、新ロコモをとめよう(35)、『暮らすめいと』、2020年2月号、中日新聞東京本社発刊
  15. 松井康素、「フレイル」はどう判定する? 握力や歩く速度が低下したら要注意、新ロコモをとめよう(36)、『暮らすめいと』、2020年3月号、中日新聞東京本社発刊
  16. 渡邉 剛、関節が痛い、kansetsu-itai.comにインタビュー記事掲載、2019.11.11 取材

先頭へ戻る

原著論文

  1. Morita Y, Ito H, Torii M, Hanai A, Furu M, Hashimoto M, Tanaka M, Azukizawa M, Arai H, Mimori T, Matsuda S. Factors Affecting Walking Ability in Female Patients with Rheumatoid Arthritis. PLOS one 13(3):e0195059 2018.
  2. Hanai A, Ishiguro H, Sozu T, Tsuda M, Yano I, Nakagawa T, Imai S, Hamabe Y, Toi M, Arai H, Tsuboyama T.      Effects of Cryotherapy on Objective and Subjective Symptoms of Paclitaxel-Induced Neuropathy: Prospective Self-Controlled Trial. JNCI Volume 110, Issue 2 2018.
  3. Fujita K, Otsuka T, Kawabata T, Sakai G, Matsushima-Nishiwaki R, Kozawa O, Tokuda H. Inhibitors of heat shock protein 90 (HSP90; HSPC) augment endothelin-1-induced heat shock protein27 (HSP27; HSPB1) through SAPK/JNK in osteoblasts. Mol. Med. Rep. 2018;17:8542-8547.
  4. Ishihara M, Saito T, Sakurai T, Shimada H, Arai H. Effect of a Positive Photo Appreciation Program on Depressive Mood in Older Adults: A Pilot Randomized Controlled Trial IJERPH 2018 Jul 12;15(7):1472.
  5. Kinoshita K, Satake S, Matsui Y, Kawashima S, Arai H. Effect of β-hydroxy-β-methylbutyrate (hmb) on muscle strength in older adults with low physical function. JARCP 2019;8:1-6.
  6. Harada-Shiba M, Arai H, Ishigaki Y, Ishibashi S, Okamura T, Ogura M, Dobashi K, Nohara A, Bujo H, Miyauchi K, Yamashita S, Yokote K; Working Group by Japan Atherosclerosis Society for Making Guidance of Familial Hypercholesterolemia Guidelines for Diagnosis and Treatment of Familial Hypercholesterolemia 2017. J Atheoscler Thromb 2018 Aug 1;25(8):751-770. doi:10.5551/jat.CR003. Epub 2018 Jun 7.
  7. Arai H, Wakabayashi H, Yoshimura Y, Yamada M, Kim H, Harada A. Chapter 4 Treatment of sarcopenia. Geriatr Gerontol Int 18 Suppl 1:28-44 2018.
  8. Kuzuya M, Sugimoto K, Suzuki T, Watanabe Y, Kamibayashi K, Kurihara T, Fujimoto M, Arai H. Chapter 3 Prevention of sarcopenia. Geriatr Gerontol Int 18 Suppl 1:23-27 2018.
  9. Shimokata H, Shimada H, Satake S, Endo N, Shibasaki K, Ogawa S, Arai H. Chapter 2 Epidemiology of sarcopenia. Geriatr Gerontol Int 18 Suppl 1:13-22 2018.
  10. Akishita M, Kozaki K, Iijima K, Tanaka T, Shibasaki K, Ogawa S, Arai H. Chapter 1 Definitions and diagnosis of sarcopenia. Geriatr Gerontol Int 18 Suppl 1:7-12 2018.
  11. Yamashita S, Masuda D, Arai H, Matsuzawa Y. Cultural Barriers in the Treatment of Dyslipidemia: A Survey of Japanese Physician Attitudes. J Atheoscler Thromb 2019 Feb 1;26(2):154-169. doi:10.5551/jat.44677. Epub 2018 May 18.
  12. Suma S, Watanabe Y, Hirano H, Kimura A, Edahiro A, Awata S, Yamashita Y, Matsushita K, Arai H, Sakurai T. Factors Affecting the Appetites of Persons with Alzheimer's Disease and Mild Cognitive Impairment. Geriatr Gerontol Int 2018 Aug;18(8):1236-1243. doi: 10.1111/ggi.13455. Epub 2018 May 29.
  13. Arai H, Yamashita S, Yokote K, Araki E, Suganami H, Ishibashi S. Efficacy and safety of pemafibrate versus fenofibrate in patients with high triglycerides and low HDL cholesterol Levels: A multicenter, placebo-controlled, double-blind, randomized trial. J Atheoscler Thromb. 2018 Jun 1;25(6):521-538. doi: 10.5551/jat.44412. Epub 2018 Apr 7.
  14. Fougere B, Cesari M, Arai H, Woo J, Merchant RA, Flicker L, Cherubini A, Bauer JM, Vellas B, Morley JE. Involving Primary Care Health Professionals in Geriatric Assessment. J Nutr Health Aging. 22(5):566-568 2018.
  15. Okura M, Ogita M, Yamamoto M, Nakai T, Numata T, Arai H. Community Activities Predict Disability and Mortality in Community-Dwelling Older Adults. Geriatr Gerontol Int. 2018 Jul;18(7):1114-1124.
  16. Sugimoto T, Sakurai T, Ono R,  Kimura A, Saji N, Niida S, Toba K, Chen LK, Arai. Epidemiological and Clinical Significance of Cognitive Frailty: a Mini Review. Ageing Research Reviews 44:1-7 2018.
  17. Fujita K, Otsuka T, Kawabata T, Kainuma S, Sakai G, Matsushima-Nishiwaki R, Kozawa O, Tokuda H. HSP90 limits thrombin-stimulated IL-6 synthesis in osteoblast-like MC3T3-E1 cells: regulation of p38 MAPK. Int. J. Mol. Med. 2018;42:2185-2192.
  18. Uematsu K, Enomoto Y, Onum T, Tsujimoto M, Doi T, Matsushima-Nishiwaki R, Tokuda H, Ogura S, Iida H, Kozawa O, Iwama T. Rac regulates the TRAP-induced phosphorylated-HSP27 release via p38 MAP kinase but not JNK from human platelets. Cell. Physiol. Biochem. 2018 Sep 13;49(4):1523-1538.
  19. Kawabata T, Tokuda H, Sakai G, Fujita K, Matsushima-Nishiwaki R, Otsuka T, Kozawa O. Repression of IGF-I-induced osteoblast migration by (-)-epigallocatechin gallate through p44/p42 MAP kinase signaling. Biomed. Rep. 2018;9:318-326.
  20. Arai H, Satake S, Kozaki K. Cognitive Frailty in Geriatrics. Clin Geriatr Med. 34(4):667-675 2018.
  21. Yamada M, Kimura Y, Ishiyama D, Nishio N, Otobe Y, Tanaka T, Ohji S, Koyama S, Sato A, Suzuki M, Ogawa H, Ichikawa T, Ito D, Arai H. Phase angle is a useful indicator for muscle function in older adults. J Nutr Health Aging, 2019;23(3):251-255. doi: 10.1007/s12603-018-1151-0.        
  22. Yamada M, Arai H. Social frailty predicts incident disability and mortality among community-dwelling Japanese older adults. J Am Med Dir Assoc, 2018 Dec;19(12):1099-1103. doi: 10.1016/j.jamda.2018.09.013.
  23. Arai H. Sarcopenia diagnostic criteria update by EWGSOP: What has been changed? Eur Geriatr Med, 2018 Dec;9(6):733-734. doi: 10.1007/s41999-018-0117-4. Epub 2018 Nov 23.
  24. Shimada H, Doi T, Lee S, Makizako H, Chen LK, Arai H. Cognitive frailty predicts incident dementia among community-dwelling older people J. Clin. Med 7(9):250 2018.
  25. Toyoshima, Araki A, Tamura Y, Iritani O, Ogawa S, Kozaki K, Ebihara S, Hanyu H, Arai H, Kuzuya M, Iijima K, Sakurai T, Suzuki T, Toba K, Arai H, Akishita M, Rakugi H, Yokote K, Ito H, Awata S. Development of the Dementia Assessment Sheet for Community-based Integrated Care System 8-items, a short version of the Dementia Assessment Sheet for Community-based Integrated Care System 21-items, for the assessment of cognitive and daily functions Geriatr Gerontol Int 18(10):1458-1462, 2018.
  26. Kitajima M, Miyata C, Tamura K, Kinoshita A, Arai H.      Job satisfaction in certified nurse specialists and certified nurses in cancer care in Japan Clin. Pract. 15(SII):977-990 2018.
  27. Torii M, Hashimoto M, Hanai A, Fujii T, Furu M, Ito H, Uozumi R, Hamaguchi M, Terao C, Yamamoto W, Uda M, Nin K, Morita S, Arai H, Mimori T. Prevalence of and factors associated with sarcopenia in patients with rheumatoid arthritis. Mod Rheumatol 11:1-7, 2018.
  28. Kawabata T, Otsuka T, Fujita K, Sakai G, Kim W, Matsushima-Nishiwaki R, Kuroyanagi G, Kozawa O, Tokuda H. HSP70 inhibitors reduce the osteoblast migration by epidermal growth factor. Curr. Mol. Med. 2018 Dec 12. doi: 10.2174/1566524019666181213112847.
  29. Matsuba I, Matsuba R, Ishibashi S, Yamashita S, Arai H, Yokote K, Suganami H, Araki E. Effects of a novel selective peroxisome proliferator-activated receptor-α modulator, pemafibrate, on hepatic and peripheral glucose uptake in patients with hypertriglyceridemia and insulin resistance. J Diabetes Investig 2018 Nov;9(6):1323-1332.
  30. Harada-Shiba M, Ako J, Arai H, Hirayama A, Nohara A, Ozaki A, Uno K, Nakamura M. Prevalence of familial hypercholesterolemia in patients with acute coronary syndrome in Japan: results of the EXPLORE-J study. Atherosclerosis 2018 Oct;277:362-368.
  31. Uematsu K, Enomoto Y, Onuma T, Tsujimoto M, Doi T, Matsushima-Nishiwaki R, Tokuda H, Ogura S, Iida H, Kozawa O, Iwama T. Rac regulates the TRAP-induced release of phosphorylated-HSP27 from human platelets via p38 MAP kinase but not JNK. Cell. Physiol. Biochem. 2018;49:1523-1538.
  32. Kawabata T, Tokuda H, Sakai G, Fujita K, Matsushima-Nishiwaki R, Kuroyanagi G, Otsuka T, Kozawa O. HSP70 inhibitor suppresses IGF-I-stimulated migration of osteoblasts through p44/p42 MAP Kinase. Biomedicines. 2018;6(4). pii: E109. doi: 10.3390/biomedicines6040109.
  33. Madoka Ikemoto-Uezumi, Akiyoshi Uezumi, Lidan Zhang, Heying Zhou, Naohiro Hashimoto, Kikuo Okamura, Yasumoto Matsui, Koji Tsukazaki, Tohru Hosoyama, Masashi Nakatani, Mitsuhiro Morita, Harumoto Yamada, Kunihiro Tsuchida, So-ichiro Fukada, Reduced expression of calcitonin receptor is closely associated with age-related loss of the muscle stem cell pool. JCSM - Rapid Communications. Volume2, Issue1.January 2019.Pages 1-13.
  34. 近藤和泉, 尾崎健一, 加藤健治, 相本啓太, 佐藤健二, 加賀谷斉, 平野 哲, 才藤栄一:フレイルにロボットは活用できるか? Modern Physician, 38, 537-540, 2018.
  35. サブレ森田さゆり、伊藤直樹、木下かほり、小嶋紀子、荒井有紀、道田愛美、山口純世、高道香織、溝神由美子、川嶋修司、谷川隆久、徳田治彦.高齢糖尿病患者に対するフレイル予防介入プログラムの評価についての検討-糖尿病教室を用いた多職種連携による介入-. 国立医療学会誌 医療, 73(1):12-19, 2019.

メディア等紹介

  1. 松井康素、運動継続で筋肉を保ち、減少を防ぐ、新ロコモをとめよう(13)、『暮らすめいと』、平成30年4月号 中日新聞東京本社発刊
  2. 松井康素、多くの人が苦しむ変形性膝関節症(1)、新ロコモをとめよう(14)、『暮らすめいと』、平成30年5月号、中日新聞東京本社発刊
  3. 松井康素、変形性膝関節症(2)、大腿四頭筋を強化、新ロコモをとめよう(15)、『暮らすめいと』、平成30年6月号、中日新聞東京本社発刊
  4. 松井康素、"座るほうがつらいんです" 座席譲るとき 断るとき あなたは?、NHK News Up(web)、2018年6月5日、https://www3.nhk.or.jp/news/html/20180605/k10011465921000.html
  5. 松井康素、松本伊代の健康ジャーニー  "カラダにい~よ!" 東海テレビ「スイッチ!」、2018年7月5日OA
  6. 松井康素、変形性膝関節症(3)、注射の有効性は?、新ロコモをとめよう(16)、『暮らすめいと』、平成30年7月号、中日新聞東京本社発刊
  7. 松井康素、変形性膝関節症(4)、「生来の装具」を強化する、新ロコモをとめよう(17)、『暮らすめいと』、平成30年8月号、中日新聞東京本社発刊
  8. 松井康素、変形性膝関節症(5)、痛みが続く場合は手術も、新ロコモをとめよう(18)、『暮らすめいと』、平成30年9月号、中日新聞東京本社発刊
  9. 松井康素、松本伊代の健康ジャーニー  "カラダにい~よ!" part.2、東海テレビ「スイッチ!」、2018年11月1日OA
  10. 松井康素、変形性膝関節症(6)、股関節周囲の筋肉を鍛える、新ロコモをとめよう(19)、『暮らすめいと』、平成30年10月号、中日新聞東京本社発刊
  11. 松井康素、関節リウマチ(1)、女性に多い自己免疫疾患、新ロコモをとめよう(20)、『暮らすめいと』、平成30年11月号、中日新聞東京本社発刊
  12. 松井康素、関節リウマチ(2)、関節修復の可能性も、新ロコモをとめよう(21)、『暮らすめいと』、平成30年12月号、中日新聞東京本社発刊
  13. 荒井秀典、松井康素、谷本正智、サブレ森田さゆり、飯塚祐美子、松本伊代の健康ジャーニー  "カラダにい~よ!" part.3、東海テレビ「スイッチ!」、2019年2月7日OA
  14. 近藤和泉、NHK WORLD、「Medical Frontiers」、国立長寿医療研究センターでの転倒予防の取り組み紹介・インタビュー、放送日時*6時間ごとに4回放送(1)2月19日(火)午前0時30分、(2)2月19日(火)午前6時30分、(3)2月19日(火)午後0時30分、(4)2月19日(火)午後6時30分
  15. 松井康素、脊柱管狭窄症(1)、歩ける距離が短くなる、新ロコモをとめよう(22)、『暮らすめいと』、平成31年1月号、中日新聞東京本社発刊
  16. 松井康素、脊柱管狭窄症(2)、神経根ブロック注射も、新ロコモをとめよう(23)、『暮らすめいと』、平成31年2月号、中日新聞東京本社発刊
  17. 松井康素、脊柱管狭窄症(3)、除圧術と固定術、新ロコモをとめよう(24)、『暮らすめいと』、平成31年3月号、中日新聞東京本社発刊

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原著論文

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  3. Morley JE, Arai H, Cao L, Dong B, Merchant RA, Vellas B, Visvanathan R, Woo J. Integrated Care: Enhancing the Role of the Primary Health Care Professional in Preventing Functional Decline: A Systematic Review. J Am Med Dir Assoc. 2017;18(6):489-494.
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  5. Yamada M, Kimura Y, Ishiyama D, Nishio N, Abe Y, Kakehi T, Fujimoto J, Tanaka T, Ohji S, Otobe Y, Koyama S, Okajima Y, Arai H. Differential characteristics of skeletal muscle in community-dwelling older adults. J Am Med Dir Assoc. 2017 Sep 1;18(9):807.e9-807.e16. doi: 10.1016/j.jamda.2017.05.011. Epub 2017 Jul 1.
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  7. Madoka Ikemoto-Uezumi, Yasumoto Matsui, Masaki Hasegawa, Remi Fiujita,Yasuhide Kanayama, Akiyoshi Uezumi, Tsuyoshi Watanabe, Atsushi Harada, A.Robin Poole, Naohiro Hashimoto. Disuse Atrophy Accompanied by Intramuscular Ectopic Adipogenesis in Vastus Medialis Muscle of Advanced Osteoarthritis Patients. Am J Pathol. 2017 Dec;187(12):2674-2685. doi: 10.1016/j.ajpath.2017.08.009. Epub 2017 Sep 15.
  8. Yoshihiro Yoshimura, Hidetaka Wakabayashi, Minoru Yamada, Hunkyung Kim, Atsushi Harada, Hidenori Arai. Interventions for treating sarcopenia: a systematic review and meta-analysis of randomized controlled studies. Journal of the American Medical Directors Association 18(6): 553.e1-553.e16, 2017.
  9. Shigeo Kawada, Atsushi Harada, Naohiro Hashimoto. Impairment of cold injury-induced muscle regeneration in mice receiving a combination of bone fracture and alendronate treatment. PLOS ONE 12(7):e0181457, 2017.
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  12. Kuroyanagi G, Tokuda H, Yamamoto N, Kainuma S, Fujita K, Ohguchi R, Kawabata T, Sakai G, Matsushima-Nishiwaki R, Harada A, Kozawa O, Otsuka T. (-)-Epigallocatechin gallate synergistically potentiates prostaglandin E2-stimulated osteoprotegerin synthesis in osteoblasts. Prostaglandins Other Lipid Mediat. 2017;128-129:27-33.
  13. Kuroyanagi G, Tokuda H, Yamamoto N, Kainuma S, Fujita K, Ohguchi R,         Matsushima-Nishiwaki R, Kozawa O, Otsuka T. Attenuation of prostaglandin E1‑induced osteoprotegerin synthesis in osteoblasts by normoxic HIF inducers. Mol. Med. Rep. 2017;15:1847-1852.
  14. Fujita K, Tokuda H, Yamamoto N, Kainuma S, Kawabata T, Sakai G, Kuroyanagi G, Matsushima-Nishiwaki R, Harada A, Kozawa O, Otsuka T. Incretins amplify TNF-a-stimulated IL-6 synthesis in osteoblasts: suppression of the IkB/NF-kB pathway. Int. J. Mol. Med. 2017;39:1053-1060.
  15. Fujita K, Otsuka T, Yamamoto N, Kainuma S, Ohguchi R, Kawabata T, Sakai G, Kuroyanagi G, Matsushima-Nishiwaki R, Kozawa O, Tokuda H. (-)-Epigallocatechin gallate but not chlorogenic acid up-regulates osteoprotegerin synthesis by bone morphogenic protein-4 in osteoblasts. Exp. Ther. Med.2017;14:417-423.
  16. Fujita K, Tokuda H, Kainuma S, Kuroyanagi G, Yamamoto N, Matsushima-Nishiwaki R, Harada A, Kozawa O, Otsuka T. Resveratrol suppresses thyroid hormone-induced osteocalcin synthesis in osteoblasts. Mol. Med. Rep. 2017;16:2881-2886.
  17. Fujita K, Tokuda H, Kuroyanagi G, Yamamoto N, Kainuma S, Kawabata T, Sakai G, Matsushima-Nishiwaki R, Kozawa O, Otsuka T. HSP90 inhibitors potentiate PGF2a-induced IL-6 synthesis via p38 MAP kinase in osteoblasts. PLoS One. 2017;12(5):e0177878.
  18. Onuma T, Tanabe K, Kito Y, Tsujimoto M, Uematsu K, Enomoto Y,  Matsushima-Nishiwaki R, Doi T, Nagase K, Akamatsu S, Tokuda H, Ogura S, Iwama T, Kozawa O, Iida H. Sphingosine 1-phosphate (S1P) suppresses the collagen-induced activation of human platelets via S1P4 receptor. Thromb. Res. 2017;156:91-100.
  19. Kainuma S, Tokuda H, Yamamoto N, Kuroyanagi G, Fujita K, Kawabata T, Sakai G, Matsushima-Nishiwaki R, Kozawa O, Otsuka T. Heat shock protein 27 (HSPB1) suppresses PDGF-BB-induced migration of osteoblasts. Int. J. Mol. Med. 2017 Oct;40(4):1057-1066. doi: 10.3892/ijmm.2017.3119. Epub 2017 Sep 1.
  20. Ozaki K, Kondo I, Hirano S, Kagaya H, Saitoh E, Osawa A, Fujinori Y, Training with a balance exercise assist robot is more effective than conventional training for frail older adults. Geriatrics & Gerontology International. 2017 Nov;17(11):1982-1990. doi: 10.1111/ggi.13009. Epub 2017 Mar 10.
  21. Hiroshi Hagino, Naoto Endo, Tetsuji Yamamoto, Atsushi Harada, Jun Iwamoto, Naoki Kondo, Tasuku Mashiba, Satoshi Mori, Junichi Nakamura, Seiji Ohtori, Akinori Sakai, Junichi Takada, Yoshiharu Kato. Treatment status and radiographic features of patients with atypical femoral fractures. Journal of Orthopaedic Science. 2018 Mar;23(2):316-320. doi: 10.1016/j.jos.2017.10.008.
  22. Watanabe Y, Arai H, Hirano H, Morishita S, Ohara Y, Edahiro A, Murakami M, Shimada H, Kikutani T, Suzuki T. Oral function as an indexing parameter for mild cognitive impairment in older adults. Geriatr Gerontol Int. 2018 May;18(5):790-798. doi: 10.1111/ggi.13259. Epub 2018 Jan 30.
  23. Teramoro T, Kai T, Ozaki A, Crawford B, Arai H, Yamashita S. Treatment Patterns and Lipid Profile in Patients with Familial Hypercholesterolemia in Japan. J Atheoscler Thromb. 2018 Jul 1;25(7):580-592. doi: 10.5551/jat.41483. Epub 2018 Jan 19.
  24. Yamada M, Arai H. Is grip strength adjustment necessary for sarcopenia diagnosis? Geriatr Gerontol Int. 2018 Mar;18(3):511-512. doi: 10.1111/ggi.13232.
  25. Eiko Takano, Keita Aimoto, Masanori Tanimoto, Toshio Teranishi, Naoki Itoh, Kenji Toba, Izumi Kondo. Comprehensive approach for community-based integrated care reduces risk of falls after fracture Journal of Frailty, Sarcopenia and Falls(2) 73-77; 2017/12
  26. Sakai G, Otsuka T, Fujita K, Kainuma S, Kuroyanagi G, Kawabata T, Matsushima-Nishiwaki R, Kozawa O, Tokuda H. Amplification by (-) epigallocatechin gallate of prostaglandin F2-stimulated synthesis of osteoprotegerin in osteoblasts. Mol. Med. Rep. 2017;16:6376-6381.
  27. Kawabata T, Tokuda H, Fujita K, Kainuma S, Sakai G, Matsushima-Nishiwaki R,   Kozawa O, Otsuka T. Resveratorol inhibits the epidermal growth factor-induced migration of osteoblasts: The suppression of SAPK/JNK and Akt. Cell. Physiol. Biochem. 2017;43:1025-1036.
  28. Kawabata T, Otsuka T, Fujita K, Kainuma S, Yamamoto N, Kuroyanagi G, Sakai G,  Matsushima-Nishiwaki R, Kozawa O, Tokuda H. Suppression by HSP90 inhibitors of BMP-4-stimulated osteoprotegerin synthesis in osteoblasts: Attenuation of p70 S6 kinase. Mol. Med. Rep. 2017;16:8507-8512.
  29. Sakai G, Tokuda H, Fujita K, Kainuma S, Kawabata T, Matsushima-Nishiwaki R, Kozawa O, Otsuka T. Heat shock protein 70 negatively regulates TGF--stimulated VEGF synthesis via p38 MAP kinase in osteoblasts. Cell. Physiol. Biochem. 2017;44:1133-1145.
  30. Kawabata T, Otsuka T, Fujita K, Sakai G, Matsushima-Nishiwaki R, Kozawa O, Tokuda H.(-)-Epigallocatechin gallate but not chlorogenic acid suppresses EGF-stimulated migration of osteoblasts: attenuation of p38 MAPK activity. Inter. J. Mol. Med. 2018 Dec;42(6):3149-3156. doi: 10.3892/ijmm.2018.3884. Epub 2018 Sep 18.
  31. Otsuka R, Matusi Y, Tange C, Nishita Y, Tomida M, Ando F, Shimokata H, Arai H.What is the best adjustment of appendicular lean mass for predicting mortality or disability among Japanese community dwellers? BMC Geriatr. 2018 Jan 5;18(1):8. doi: 10.1186/s12877-017-0699-6.
  32. Makizako H, Tsutsumimoto K, Shimada H, Arai H, Social frailty among community-dwelling older adults: Recommended assessments and implications, AGMR, 2018 Mar;22(1):3-8. doi:10.4235/agmr.2018.22.1.3. Epub 2018 Mar 31.
  33. Tokuda H, Kuroyanagi G, Onuma T, Enomoto Y, Doi T, Iida H, Otsuka T, Ogura S, Iwama T, Kojima K, Kozawa O. Ristocetin induces phosphorylated-HSP27 (HSPB1) release from the platelets of type 2DM patients: Anti-platelet agent-effect on the release. Biomed. Rep. 2018;8:365-372.
  34. Sable-Morita S, Sugiura S, Uchida Y, Tanikawa T, Tokuda H, Arai H. Relationship between hearing impairment and frailty in older patients with diabetes mellitus. J. Aging Geriatr. Med. 2018;2:1. doi:10.4172/2576-3946.1000114.
  35. Sakai G, Tokuda H, Yamamoto N, Matsushima-Nishiwaki R, Fujita K, Kawabata T, Kozawa O, Otsuka T. Association of HSP22 with mTOR in osteoblasts: regulation of TNF--stimulated IL-6 synthesis. FEBS Lett. doi:10.1002/1873-3468.13028.
  36. 平野裕滋, 藤田 秀, 平野啓祐, 阿部 潤, 杉浦加奈子, 市原 薫, 松井康素. 日本転倒予防学会誌.4(1):43-51.四日市市における地域高齢者の転倒実態~2008年から2015年までの8年間の救急出動記録より~Rate of Falls by Community-Dwelling Older Adults in Yokkaichi City based on Emergency Dispatch Records for Eight Year from 2008 to 2015.
  37. 渡邉剛,松井康素,竹村真里枝,飯田浩貴. 脛骨高度欠損症例に対する、NexGen/PERSONAシステム併用による人工膝関節置換術,中部整災誌. 875-876,60巻(2017) 5号.

メディア等紹介

  1. 松井康素、いつまでも元気で動けるように、新ロコモをとめよう(1)、首都圏の生活情報紙、『暮らすめいと』、平成29年4月号、中日新聞東京本社発刊
  2. 松井康素、ロコチェック一番苦手は?、新ロコモをとめよう(2)、『暮らすめいと』、平成29年5月号、中日新聞東京本社発刊
  3. 松井康素、ロコモ予防に筋肉を鍛える、新ロコモをとめよう(3)、『暮らすめいと』、平成29年6月号、中日新聞東京本社発刊
  4. 松井康素、かかと上げ下げで筋力アップ、新ロコモをとめよう(4)、『暮らすめいと』、平成29年7月号、中日新聞東京本社発刊
  5. 松井康素、運動でサルコペニア予防、新ロコモをとめよう(5)、『暮らすめいと』、平成29年8月号、中日新聞東京本社発刊
  6. 松井康素、ロコモは現代の国民病になるか、新ロコモをとめよう(6)、『暮らすめいと』、平成29年9月号、中日新聞東京本社発刊
  7. 荒井 秀典、長生き 健康に暮らしてこそフレイルについて紹介、2017年8月15日、朝日新聞
  8. 原田 敦、ロコモティブシンドロームについての対談、1面記事、2017年9月18日、中日新聞
  9. 松井康素、ロコモは現代の国民病になるか、新ロコモをとめよう(7)、『暮らすめいと』、平成29年10月号、中日新聞東京本社発刊
  10. 松井康素、運動と食事で骨粗しょう症予防、新ロコモをとめよう(8)、『暮らすめいと』、平成29年11月号、中日新聞東京本社発刊
  11. 松井康素、無自覚の「いつの間にか骨折」も、 新ロコモをとめよう(9)、『暮らすめいと』、平成29年12月号、中日新聞東京本社発刊
  12. 松井康素、太ももの骨折はもっとも要注意、新ロコモをとめよう(10)、『暮らすめいと』、平成30年1月号、中日新聞東京本社発刊
  13. 松井康素、「バランス力の低下」を防ごう、 新ロコモをとめよう(11)、『暮らすめいと』、平成30年2月号、中日新聞東京本社発刊
  14. 松井康素、「加齢」「不動」で筋肉が減っていく、新ロコモをとめよう(12)、『暮らすめいと』、平成30年3月号、中日新聞東京本社発刊
  15. 松井康素、『春に向けてなまった体の回復術』、東海テレビ「スイッチ!」、平成30年3月1日OA

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